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Themed collection Coronavirus articles - free to access collection

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Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

新年英文祝福语大全Best wishes for the year to come! 恭贺新禧! Good luck in the year ahead! 祝吉星高照! May you come into a good fortune! 恭喜发财! Live long
以下是其中最值得期待的10部,我们相信这10部电影都将成为票房宠儿,值得反复欣赏。

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

或许纯粹是巧合,但Magento首位产品经理蒂姆o舒尔茨也刚刚加入Bigcommerce,出任产品管理高级副总裁。舒尔茨近年来担任谷歌Shopping Express、Wallet等服务的战略合伙和商业发展高管,未来将专注于Bigcommerce的一站式体验,将电子商务和实体零售更好地结合起来。“消费者想要无缝化体验,”他说。
In the field of the best 85 business schools in Europe, HEC Paris remains in second place behind LBS, while Insead, the international school based in Fontainebleau, France, climbs two places to third.

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

Open Access Perspective

Soft matter science and the COVID-19 pandemic

节目1 开场曲《欢歌贺新春》,中央电视台48位主持人

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

金州勇士队的控球后卫史蒂芬·库里表示,自2013年开始,他每年都会前往中国,而中国的篮球迷也都非常支持他。

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

The performance was his worst so far this season, yet, frankly, it wasn't too dissimilar from those that preceded it. In his 20th NBA season, the 37-year-old Bryant has looked his age.
The Lord of the Rings trilogy. The amount of time before I need an oil change. My cell phone's battery charge. What do all of these things have in common? The
埃马纽埃尔马克龙(Emmanuel Macron)会得到德国总理安格拉默克尔(Angela Merkel)对欧元区预算的承诺吗?
4Germany

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

Among the year’s biggest surprises was the plunge in gasoline pries. Economists differed on the economic impact—money in the pockets of consumers offset by declines in exploration and drilling activity—but everyone agreed that it was bearish for small cars and hybrids. The combination of cheap gas and a steep sticker price made the Cadillac ELR the runaway winner of the most disliked car of the year award. Only 155 of the Volt-based $80,000 cars found buyers in November.
For: Oldman's seemingly effortless embodiment of the wartime leader has won almost universal
具体来说,广电总局表示,2016年中国票房总额达到457亿元人民币(约66亿美元),比2015年增长3.7%。
“这让编辑以为文章发送给了该学科真正的评审人。我们与真正的评审人进行调查和沟通后,他们确认并没有对论文做过评审。

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

Shanghai is the most popular destination for new job seekers, followed by Shenzhen, Guangzhou and Beijing. Provincial capitals cities in central and western regions are also among the top choices for the new graduates.

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

4. Manufacturing won't save the economy.

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

For newcomers, these changes provide fresh housing options. But for residents, they can spell displacement. The same is true for shops such as De Robertis Pasticceria and Caffe in the East Village, which just closed after a 110-year run. And next year, the Union Square Cafe will likely conclude its 30 years in Union Square.
单词confident 联想记忆:

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

In the past 12 months, more than 20 provinces have introduced policies to encourage students to start their own companies by allowing them to quit studying but keep their student status for two to eight years. However, many industry insiders insist that students complete their studies and work a few years first.
最佳迷你剧集/电影类编剧:D?V?蒂文森斯(D.V. DeVincentis),《美国罪案故事:公诉辛普森》,“玛西亚,玛西亚,玛西亚” (The People v. O. J. Simpson: American Crime Story, "Marcia, Marcia, Marcia")

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

Complying with the law may prove challenging, even if improvements ultimately reduce long-term costs. In addition, 2015 is the deadline for buildings to convert from No. 6 heating oil to No. 4 oil, which is less polluting.
从“高跟鞋门”到“金棕榈狗狗奖”(Palm Dog),再到迅速走红的“老爹身材(Dad bod)”,戛纳电影展的这12天,真是令人眼花缭乱。随着电影节进入尾声,英国广播公司回顾了本届戛纳影展上的九桩事。

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

n. 品质,特质,才能
Targeted poverty alleviation
从eBay的Magento电子商务系统、IBM和NetSuite等知名企业到规模较小的Shopify和Volusion等,很多科技公司都希望从中分一杯羹。但相对冷门的Bigcommerce正在悄悄引发关注并窃取市场份额。它吸引了超过7,500万美元的风投资本,其中4,000万美元来自企业家史蒂夫o凯斯的Revolution Growth公司。
*最佳真人秀主持:鲁保罗?查尔斯(RuPaul Charles),《鲁保罗变装皇后秀》(RuPaul’s Drag Race, Logo)

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

年度最佳合唱:埃里克·丘奇、杰森·阿尔丁、卢克布·莱恩《The Only Way I Know》

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

确实,现在的保罗更大更强壮了,但是,现在的他脸蛋和高中的自己一样。在高中的时候,保罗甚至就有了自己标记性的胡须。
To Anita Eerland and Rolf Zwaan [THE NETHERLANDS] and Tulio Guadalupe [PERU, RUSSIA, and THE NETHERLANDS] for their study “Leaning to the Left Makes the Eiffel Tower Seem Smaller."

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

扎实推进“一带一路”建设。

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

“Why do we keep getting so many record-warm years?” Dr. Schmidt asked in an interview. “It’s because the planet is warming. The basic issue is the long-term trend, and it is not going away.”

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
From the themed collection: 租赁市场年尾如何“度淡”?
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

这是光明的季节,也是黑暗的季节……
Andrew Bargery, campus and schools engagement leader at PwC, says Teach First graduates stand out: “They have already worked in a professional envir-onment and have professional maturity and are good at building relationships.”
201110/156989.shtmlThe Victoria's Secret Fashion Show just taped, and this year's was one of the most elaborate ever.
在你面试应聘者的时候,有些人得分较高,你认为应该他能得到这份工作,但是招聘主管却改掉分数,招那些他喜欢的人。

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

出演《美国队长3:英雄决裂》的斯嘉丽-约翰逊排名第三,收入为2500万美元,比去年下降了近30%。
就算利润率更低(比如40%),并且替代率为1/3(即全价iPhone的客户流失三分之一),低价iPhone也能提高苹果的营收和毛利润(见上表)。
依然年轻
It was an incredible achievement for SpaceX. The first stage rocket of one of its Falcon 9 launchers, having successfully lofted cargo to the International Space Station, managed to turn itself around, bleed off the enormous kinetic energy it had acquired while its main engines were burning, fly back down to Earth and land vertically - with balletic precision - on a rather tiny looking robotic barge floating somewhere in the Atlantic.
“我头发都白了,一半为了房价,一半为了(你们)记者。”

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

“我是一个医生。说实话,一个人的健康首先与吃、喝与空气有关,如果这三样不好,再提什么样的发展都没有用!”
《帕丁顿熊2》

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
From the themed collection: 借口房贷新政 折定金赔违约金
Critical Review

The role of biosensors in the detection of emerging infectious diseases

2017已经是詹姆斯在联盟中的第十四个赛季,但他的场均助攻和篮板竟然还创下了职业新高。在这个赛季的前两个月里,他拿出了整个职业生涯最好的三分表现,但鉴于这已经被各方专家们讨论和剖析,并且被媒体广泛的报道了,我在这里就不加赘述了。

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

Wal-Mart U.S. president and CEO Bill Simon

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
From the themed collection: 广西4批次水泥产品质量不合格
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

7. 《出局:禁止接触》(Out 1: Noli Me Tangere),导演:雅克·里维特(Jacques Rivette)。
An EMBA also boosts corporate careers. “The skills I acquired were key to my promotion,” said one graduate. A fifth are now chief executives, managing directors or board members three years after graduation. Average salaries were up 52 per cent from $114,000 before the programme to $175,000 five years later.
? President Obama declared a "major disaster" in New York and New Jersey. Flooding devastated the coast and more than 2.3 million lost power. The National Guard rescued hundreds from flooding in New Jersey. The governor, Chris Christie, a Republican, said the damage was "unthinkable". He praised the "outstanding" co-operation he had received from Obama.
201001/93691.shtml重点单词

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

全球肥胖率上升的前因后果。
Phil Baty, editor of the rankings, said: "it seems that China's relentless march up the global league tables has stalled, after making major gains in recent years. This new data shows just how hard it is for emerging powers to break into the traditional global elite."
据中国电影监察机构日前表示,2016年中国票房总额有望超过2015年的440亿元人民币(折合68亿美元)。
No.2: Another Reason for Staying in Bed

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

A network of walking and biking trails leads to other lakeside neighborhoods and to downtown, which is about 15 minutes by bicycle and 10 by car. The Walker Art Center and other museums are nearby. Hockey and skating are popular on the lakes in winter; canoeing, swimming and fishing in the summer.
Some industries will likely pick up faster than others. Industries such as construction and manufacturing will probably begin to hire sooner. Retail, tourism, and hospitality, which depend entirely on consumer spending, will probably be among the last to recover.

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

500个品牌来自28个不同国家,其中近半(227个)来自美国。
在几代人之中,工薪阶层的白人受到双重赐福:他们既拥有种族所带来的特权地位,也受惠于经济的繁荣发展。
现在的勇士队已经是NBA历史上最好的球队之一,你可以把他们的冠军阵容和NBA历史上的任何一支球队相提并论,因为他们打出了有史以来最好的季后赛表现。但同时也有一个“篮球”的问题。如果历史上最好的或者第二好的球员都没有机会对抗这支球队,那对这项运动的竞争力意味着什么呢?到目前为止,幸运的是这个问题并没有凸显出来,这可多亏了一个非常狂野的休赛期,但问题仍然存在:当一个最高水品的竞技体育联赛缺乏真正的竞争时,它会发生什么?
有了正确的工具,你就会发现自己的工作生活变得更加高效。(财富中文网)
由施普林格自然集团出版的杂志《肿瘤生物学》上周宣布,调查显示,这107篇论文的同行评审过程存在问题,因此已被撤稿。

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

Stanford Graduate School of Business in California rises from fifth place in 2016 to second, a position it last held in 2014. The Wharton School of the University of Pennsylvania is in third place.
单词ballroom 联想记忆:
The latest commerce ministry figures do not include real estate purchases by individuals, many of whom exploit loopholes in China's capital control regime to obtain foreign currency. But the foreign exchange regulator has recently moved to close such loopholes, notably by tightening control of forex purchases by individuals, who are allowed to exchange $50,000 worth of renminbi for foreign currency each year.

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
From the themed collection: 房产调控政策应因城施策
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

提问
《狼厅》(Wolf Hall),PBS,4月5日播出。这一季最引人注目的选角,《国土安全》(Homeland)的主演达米恩·刘易斯(Damian Lewis)将在该剧中饰演亨利八世,两获托尼奖的马克·里朗斯(Mark Rylance)将饰演托马斯·克伦威尔(Thomas Cromwell),这部经典改编剧改编自希拉里·曼特尔(Hilary Mantel)的畅销历史小说。

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
From the themed collection: 北京:统筹实施土地资源整理
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
From the themed collection: LED商业照明规模将达136.88亿元
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

就在一个月前,近200个国家的政府在巴黎达成了一项新的气候协议,目标是阻止全球气温比工业化前水平上升2摄氏度以上,最好限制在1.5摄氏度以内。
The government-sponsored students have signed an agreement that says they are required to reimburse the government if they do not return home after completing their studies, said Xiong Binqi, vice president of 21st Century Education Research Institute.
碧昂斯与妮琪·米娜(Nicki Minaj),《完美》(Flawless, Remix),Parkwood/Columbia

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

7. “The Kindergarten Teacher” In his tough, weird knockout, the Israeli director Nadav Lapid spins the story of a teacher’s obsession with a child poet to create a savage portrait of fanaticism and its costs.
The programme is ranked second for career progress three years after graduation. Tiemba’s graduates number only about 250 so far, making them an elite group.— LaurentOrtmans
Mr Koepke warns that this could easily be upset by the Fed.

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

沃伦·巴菲特自2014年以来再次排名第二,净资产由去年的608亿美元增加到756亿美元。

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

游泳、花样游泳、跳水、皮划艇、激流回旋、静水、赛艇、帆船、水球

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

“这是关于‘我们是谁’的基本问题,”伦敦大学伯克贝克学院的政治学教授埃里克?考夫曼(Eric Kaufmann)说,“作为这个国家的一员意味着什么?它是否已经不再是‘我们’的国家?——‘我们’是指占多数的民族。
The End of the Road

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

8.A New iPhone
A report by human resources website Zhaopin released recently found that only 3.1 percent of students expecting to graduate in July said they will start their own business, down from 6.3 percent in 2015.
感情破裂搜索排行居首的是贾斯汀?比伯和赛琳娜?戈麦斯分手的消息,此外维多利亚?彭德尔顿打败了乔治亚?索帕,成为搜索次数最多的真人秀选手。
劳瑞斯蒂尔

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

在这个力求避免任何歧视的态度的年代,年轻一代开始不满邦德的大男子主义态度和不健康的生活方式,因此赫洛维兹引入了一系列会指出邦德错误的新人物。
temporary

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

杨燕绥说道,为确保该计划顺利进行,中央政府必须夯实统筹基础养老金,做大职业年金,管好个人账户。
200911/88510.shtml

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

从“高跟鞋门”到“金棕榈狗狗奖”(Palm Dog),再到迅速走红的“老爹身材(Dad bod)”,戛纳电影展的这12天,真是令人眼花缭乱。随着电影节进入尾声,英国广播公司回顾了本届戛纳影展上的九桩事。

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
From the themed collection: 2014年中国家居行业八大猜想
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

2. Dunkirk
Goldie Blox:
An investigation is continuing into how La La Land was wrongly named Best Picture rather than the triumphant Moonlight.
1. You became a LinkedIn superstar overnight。

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

The 2017 grads of Tsinghua University earn an average salary of 9,065 yuan per month, according to the survey released by xinchou.cn, an internet salary survey and report provider.
但近2/3(65%)的福音派白人新教徒认为这些暴风雨是“末日”即将到来的证据,就如《圣经》中预言的那样。

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

以下是人们经常用来描述自己的一些句子。
As we pointed out earlier, we've long been able to restore hearing to the deaf, but restoring sight to the blind is a much more complicated matter. When people lose their sight, their retinas no longer send signals from their photoreceptors to their brains. To make an artificial eye, we'd need to understand how the retina processes those signals, and that's a code scientists just haven't been able to crack.
['k?midi]

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

否则,就应该交易考辛斯还有在过去的两个赛季里签下的其他的老将了。
Analysts survey by Bloomberg expected a rise to 1.9 per cent in January.
与此同时,中国12月消费者物价指数(CPI)略升至1.5%,11月为1.4%,为5年低点。

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

4. Your co-worker blabbed。
sincerely

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

In July, the government made the first stab at regulating internet finance when 10 agencies, including the central bank, the banking regulator and the securities regulator jointly issued guidelines that provide an official definition of “internet finance” and specify which agencies are responsible for regulating which types of internet financial institutions.
The cost of living the Australian dream has surged with Sydney and Melbourne among the five most expensive cities in the world, outstripping most European and US locations, according to an annual survey released on Monday.
Emma Thompson, a two-time winner for Howards End and Sense and Sensibility, famously keeps hers in the loo: “They look far too outré anywhere else. They’re great big, gold, shiny things.” She’s not alone – Susan Sarandon, Lionel Richie and Sean Connery all claim to keep their golden fellas alongside their bidets and baths.

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

Beijing is banning Chinese tour groups from visiting South Korea, the latest retaliation against the planned Korean deployment of the US-built Thaad missile shield, according to two people with knowledge of the plans.
Meanwhile, villages within the city's boundaries will be overhauled and low-end manufacturers and logistics companies removed.

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

中国早已超越了俄罗斯成为紧随美国之后的世界第二大强国。
扫盲:Illuminati字面意思为“先觉者”,是启蒙运动时期的一个巴伐利亚秘密组织,成立于1776年5月1日。它的成员中包括文学巨匠歌德和哲学家海德这样声名赫赫的人物,但它存在的时间却十分短暂。我们熟知的Illuminati(光明会)最早的首脑,正是大名鼎鼎的伽利略。他非常喜爱对称物,于是另一位光照派成员——艺术大师贝尔尼尼便为伽利略设计了一件杰作。他将16世纪时人们认为组成世界的四大元素:土(earth)、水(water)、火(fire)、气(air)以及Illuminati(光明会)这五个原本并非对称字的单词设计成了对称的文字,即在倒转180度之后与原来的形状一模一样的文字图案。
['t?ksik]

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

There is a salary gap of nearly 22 per cent between male and female graduates three years after they finished their courses, $90,000 compared to $73,000. That gap had been 17 per cent whenstudents first graduated, so thisdifference has widened over time(see chart).

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

n. 外表,外貌,出现,出场,露面
排放量去年的增幅比过去十年中2.5%的平均增长率略低,而且排放量增幅之所以下降,很大程度上是由中国经济增长放缓所引起的。中国是世界上最大的温室气体排放国。可能还需要再花一到两年时间,才能弄清楚中国排放量的增长究竟有没有放缓,还是最近数年那种极高的增速仍会持续。

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

The Wizards need to surge ASAP if they want to stay in this. We saw what happened last year when they waited too long to get it together.
根据贝克?麦坚时国际律师事务所(Baker & McKenzie)和荣鼎咨询(Rhodium Group)的一份报告,2015年中国国有企业和民营企业在欧洲(包括挪威和瑞士,以及欧盟)总共投资了230亿美元,创历史新高;在美国投资了150亿美元。

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

The report also showed regions with a better-developed economy produce more cyberstars, with Beijing, Shanghai, Guangdong, Jiangsu and Zhejiang leading the rankings.
会计和咨询业

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

最差运动员精神奖
‘Our hope is that the Worst Passwords of the Year list will cause people to take steps to protect themselves online.’

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

4. 学会自我推销。

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

Imports grew 6.7 per cent year-on-year to $152.2bn after falling 1.4 per cent the previous month, according to China’s General Administration of Customs, defying a median forecast predicting contraction would worsen to 1.9 per cent.
2016年上半年,《实验心理学》期刊刊登了一项研究,题为“绘画效应:帮你在无障碍回忆的过程中构筑可靠强大的记忆力”。虽然这篇文章的题目看起来有点长、有点复杂,但是它证明的观点其实很简单,即把单词画出来的记忆方式能够建立更为优质牢固的记忆。研究的主持人进行了一个简单任务实验,在实验中,一位参与者要求画出简单的单词,比如常见的水果,接着,他被要求回忆自己画的是些什么单词。另一些参与者被要求重复朗读给出的单词。
如果你想把内容写作工作的一部分或全部外包出去,那么你首先要确保你获得的内容是原创的。你可以把内容粘贴到CopyScape的分析工具,然后就能立刻知道这些内容是否为原创。
“你们可以选择自己喜欢的休假方式,”他写道,并建议人们“旅行、参加慈善项目、与家人共享天伦之乐,或只是利用假期充电和调整心态”。

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

奥巴马将迎来第二个任期,摆在他面前的任务依然很艰巨:如何处理1万亿美元的高额年度财政赤字,如何削减高达16万亿美元的国债,如何改革开支高昂的社会事业,如何应对党派斗争激烈陷入僵局的美国国会等等。

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

眼看11月就要过去了,正如我周一写的那样,往年经验表明,9支球队很有可能已经被踢出季后赛地竞争行列了。然而,他们中没有一支球队表明要摆烂。
“We sincerely apologize to Moonlight, La La Land, Warren Beatty, Faye Dunaway, and Oscar viewers for the error that was made during the award announcement for Best Picture. The presenters had mistakenly been given the wrong category envelope and when discovered, was immediately corrected.”
"Based on experience from previous years, the number of applicants could sharply increase as the application window closes, especially during the last three days of application," an unidentified official with the Ministry of Human Resource and Social Security said on the ministry's website.

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

2. Google Docs
Apple Inc., Alphabet Inc.'s Google, and Coca-Cola Co. topped the list of the world's 100 most valuable brands in 2016, while technology and automotive brands dominated the overall rankings, according to a new report from brand consultancy Interbrand.

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

The Atlanta-based group expects sales, adjusted for acquisitions, divestitures and currency fluctuations, to rise 3 per cent, compared with its earlier forecast of between 4 per cent and 5 per cent.
10. "Arrow" (2.2 million)

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
From the themed collection: 专家聚焦完善住房保障体系
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

或许,在纽约尼克斯夺取NBA总冠军的道路上,缺失的关键就是甜瓜(安东尼的昵称)。噢,不,等等,林书豪才是他们欠缺的一环。然而,无论怎样,甜瓜不会妨碍尼克斯的冠军梦。

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

5. Confirmation of the discovery of a nearby habitable planet
"Even though these two researchers worked independently of one another, the combination of Shapley's basic theory and Roth's empirical investigations, experiments and practical design has generated a flourishing field of research and improved the performance of many markets," the academy said.
单词capacity 联想记忆:

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
From the themed collection: 毕业租房要防“坑”
Paper

Length-scale dependence of protein hydration-shell density

Beauty and Evolution
现金全款购房者。难以取悦的贷款人。暴涨的价格。匮乏的挂牌信息。这些现实,都困扰着购房者,使找房子的过程让人倍受打击。不幸的是,在新的一年,购房者们可能依旧需要在卖方市场里打拼。
公司:网络投票公司Everyone Counts
《边桥谜案》(The Bridge),Hulu,周五播出。这部丹麦、瑞典合拍的犯罪剧即将迎来第二季(FX的同名剧集就是根据它改编的,最近刚刚被砍掉),新的一季仍与连接两个乡村的奥莱桑德桥有关。

Graphical abstract: Length-scale dependence of protein hydration-shell density
From the themed collection: 河北省推广67种绿色建材产品
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

Aoki-san is a pleasure to work withon storyboard. With Aoki-san on the team it feels like a sure thing. The visionof these animations will be perfect.
值得一提的是,优步和特斯拉也未能上榜。“优步和特斯拉都在创新,但用专利数量、成功、全球化和影响力进行衡量,都不足以上榜,”Stembridge说道。“还有,这两家公司在2010-2014年这段时间也没有获得超过100项的专利技术,从而达到该榜单要求。”

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

Police, who raided the criminal operation, said they also found beef tripe, cartilage and other out-of-date animal organs - all of which had been smuggled across the border from neighbouring Vietnam. In total 20 tonnes of illegal meat was seized.
11月初,中国政府要求一些通过离岸实体操作的境外收购需得到监管部门批准,进一步收紧了对境外投资的管控。
桑尼伯恩和他的父母以及11岁的妹妹朱莉娅住在佛蒙特州的布里斯托尔,他正在寻求民主党的提名。

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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Given a choice, Chinese university graduates prefer to find employment rather than start a company.
导演贝尼特·米勒(Bennett Miller)认为卡瑞尔是饰演杜邦的合适人选,但不想让观众一眼就认出他来。他要求造型师比尔·科森(Bill Corso)改变卡瑞尔的外貌。

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